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Quiz 1

This activity contains 11 questions.

Question 1
1 What is the approximate pKa of the α-carbon between a ketone carbonyl group and an ester carbonyl group of a β-keto ester?
End of Question 1

Question 2
2 What is the pKa of the α-carbon of an ester?
End of Question 2

Question 3
3 Which of the following compounds is the most acidic?
End of Question 3

Question 4
4 The pKa of the methylene group of 2,4-pentanedione, CH3-C(=O)-CH2-C(=O)-CH3 is 8.9. Which statement best describes the charge distribution in the anion formed by deprotonation?
End of Question 4

Question 5
5 Which of the following is a true statement?
End of Question 5

Question 6
6 Which of the following statements is not true about base-catalyzed alpha-substitution reactions?
End of Question 6

Question 7
7 What product is formed when 3-pentanone is dissolved in D2O that contains some -OD?
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Question 8
8 What product is formed when acetone undergoes an aldol condensation?
End of Question 8

Question 9
9 The product of a Claisen condensation is
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Question 10
10 Which of the following steps does not occur in an acid-catalyzed alpha-substitution reaction?
End of Question 10

Question 11
11 Acetophenone, Ph-C(=O)-CH3, undergoes an aldol condensation when treated with sodium hydroxide. Explain why water is lost even if the initially formed addition product is not heated.
End of Question 11

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