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Extensions of Mendelian Genetics
Self-grading Problems

1 .       Which is not true about wild-type alleles? [Hint]



2 .       In some cases that appear to exhibit complete dominance, evidence suggests that these may really be cases of incomplete dominance. What is the basis of this evidence? [Hint]



3 .       Multiple allelism can only be studied in populations because [Hint]



4 .       The Bombay phenotype illustrates [Hint]



5 .       When mutations occur in genes whose products are essential to an organism's survival [Hint]



6 .       In which type(s) of inheritance does the genotypic ratio match the phenotypic ratio? [Hint]



7 .       Thomas H. Morgan first came to realize that inheritance of genes on the sex chromosomes differed from genes on the autosomes because of his observation that [Hint]



8 .       In sex-influenced inheritance, the phenotypes are controlled by autosomal genes whose expression is affected by the [Hint]



9 .       When the expression of one gene pair masks the expression of another gene pair, this is referred to as [Hint]



10 .       What is the difference between incomplete dominance and codominance? [Hint]



11 .       The following interactions are found in mice. The albino allele (a) eliminates all color in homozygotes and is recessive to the normal pigment allele (A). The black allele (b) causes the normal gray-brown agouti coat color to be much darker and is recessive to the normal agouti allele (B). A mouse of genotype Aabb will [Hint]



12 .       In the ABO blood types, what combination is not possible? [Hint]



13 .       In snapdragons, when a red flower is crossed with a white flower, all the progeny are pink. This type of inheritance is called [Hint]



14 .       Certain combinations of alleles lead to spontaneous abortion of a developing fetus. In this case, the normal Mendelian ratios appear to be altered because [Hint]



15 .       In some cases of complete dominance, heterozygotes have a reduced level of the particular enzyme in question. Why is this still considered complete dominance? [Hint]



16 .       To prevent erythroblastosis fetalis, if an Rh-negative mother gives birth to an Rh-positive child, [Hint]



17 .       The mother of a household develops Huntington disease in her forties. The father has been tested and does not carry the gene. They have three children (two daughters and one son), each of whom has a 50% probability of inheriting the disease. This peculiar inheritance pattern is due to a [Hint]



18 .       In Drosophila, two mutations, black body and ebony body, give similar phenotypes. Both are recessive mutations that alter the normal phenotype, a gray-brown body. When a black strain is crossed with an ebony strain, all the offspring have the normal body color. This indicates that [Hint]



19 .       A mother who is blood type AB has a child who is AB also. A potential father is blood type O. A well-informed geneticist concludes that [Hint]



20 .       Genetic anticipation refers to the phenomenon which shows [Hint]



21 .       A recessive mutation was discovered in a small island population (1,000 people). The mutation was observed in the heterozygous state, but never in the homozygous state. What is a possible explanation for this observation? [Hint]



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