Multiple-choice Quiz

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Chapter 21

This activity contains 7 questions.

Oncogenes __________.

	are both derived from proto-oncogenes and induce uncontrolled cell proliferation
	are tumor suppressor genes
	are derived from proto-oncogenes
	induce uncontrolled cell proliferation
	are viral genes

The function of the ras gene family involves __________.

	signal transduction
	tumor suppression
	chromosome segregation
	cell cycle control
	chromatin condensation

Cancer is best described as __________.

	a genetic disorder at the cellular level
	a genetic disease at the somatic cell level
	a genetic disease at the gametic cell level
	an environmental disease at the gametic cell level
	a bacterial disease at the somatic cell level

Apoptosis represents genetically programmed __________.

	determination
	tumor suppression
	cell death
	proto-oncogene conversion
	differentiation

Ionizing radiation, viruses, and chemicals are all examples of __________.

	carcinogens
	precursors to oncogenes
	tumor suppressors
	environmental hazards

and are two classes of proteins known to regulate the cell cycle checkpoints.

	Protein kinases/cyclins
	Cyclin-dependent kinases/cyclins
	p53/polymerases
	Ligase/polymerases
	Protein kinases/ATP synthase

Why is familial retinoblastoma known to be inherited as an autosomal dominant trait when the responsible gene is recessive?

	This recessive gene needs only one copy to express this phenotype.
	People with this mutation are always homozygous for this allele.
	If you are born with one allele mutated in every cell, the chance that the other allele will be mutated in one of the retinal cells is extremely high.
	Retinoblastoma was mischaracterized originally when it was called an autosomal dominant trait.

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Multiple-choice Quiz

Oncogenes __________.

The function of the ras gene family involves __________.

Cancer is best described as __________.

Apoptosis represents genetically programmed __________.

Ionizing radiation, viruses, and chemicals are all examples of __________.

__________ and __________ are two classes of proteins known to regulate the cell cycle checkpoints.

Why is familial retinoblastoma known to be inherited as an autosomal dominant trait when the responsible gene is recessive?

and are two classes of proteins known to regulate the cell cycle checkpoints.