Evolutionary Analysis

Chapter 5: Mendelian Genetics in Populations I: Selection and Mutation

Review

This self-graded quiz provides a quick check of your understanding of chapter material, including the ability to analyze data and apply concepts.

1. Selection will lead to evolutionary change [Hint]

2. A hypothetical population has a gene of interest which has two alleles, A1 and A2. Let p represent the frequency of A1 and q the frequency of A2. Let P represent the frequency of A1A1 homozygotes, Q represent the frequency of heterozygotes, and R represent the frequency of A2A2 homozygotes. Which of the following is a valid test of whether or not the population is in Hardy-Weinberg equilibrium? [Hint]

3.

A population has a gene with two alleles, B1 and B2. Following the standard conventions used in the Hardy-Weinberg equations, correctly match each phrase with the correct symbol. [Hint]

Using the pulldown boxes, match each item on the left to the corresponding item at right.

A. q2
B. q
C. 2pq
D. p
 [Hint]
 [Hint]
 [Hint]
 [Hint]
 

4. According to the basic model of mutation/selection balance, if selection is strong and mutation rate is low, the equilibrium frequency of the allele in question will be _____; when selection is weak and the mutation rate is high, the frequency of the allele will be relatively _____. [Hint]

5. Briefly explain the major flaw in the "logic" of forced sterilization to reduce the frequency of feeblemindedness. [Hint]

To create paragraphs in your essay response, type <p> at the beginning of the paragraph, and </p> at the end.

6. List and briefly describe the assumptions of the Hardy-Weinberg equilibrium principle. [Hint]

To create paragraphs in your essay response, type <p> at the beginning of the paragraph, and </p> at the end.

7. Over the long term, selection favoring the rare phenotype in a polymorphic population (i.e., negative frequency dependent selection) will _____ genetic diversity in the population. [Hint]

8. Pier and his colleagues have suggested that cystic fibrosis is maintained at relatively high levels in people of European ancestry because of heterozygote superiority; specifically, he proposposes that heterozygotes are more resistant to typhus than are the dominant homozygotes. Evidence in favor of this hypothesis includes which of the following findings? [Hint]

9. The Hardy-Weinberg equilibrium principle yields which of the following conclusions? [Hint]

10. The HIV epidemic is unlikely to lead to an increase in the CCR5 delta-32 allele over the short term because [Hint]

11. When selection acts against a recessive allele that is initially at high frequency in a population, [Hint]

12. When selection favors heterozygotes over homozygotes, [Hint]

13. When selection favors homozygotes over heterozygotes [Hint]

14.

You have sampled a population and determined that it has two alleles (D1 and D2) of the alcohol dehydrogenase gene. Of the individuals you sampled, 50 are homozygous for A1, 20 are heterozygous, and 30 are homozygous for A2. The population may or may not be in Hardy-Weinberg equilibrium. Match each symbol or phrase below with the correct number. [Hint]

Using the pulldown boxes, match each item on the left to the corresponding item at right.

A. .50
B. .16
C. .60
 [Hint]
 [Hint]
 [Hint]
 

Answer choices in this exercise are randomized and will appear in a different order each time the page is loaded.
 




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