Biological Science

Chapter 17: Genetic Engineering and Its Applications

Research Links

Chapter 17 discussed a popular news item—genetic engineering. Only a few short years after learning what DNA is, scientists now manipulate the information in the DNA of plants and animals in order to improve life that is of agricultural, medical, or technological interest to society. This scientific prowess has set off a series of philosophical, religious, and scientific debates on whether or not humans should tamper in the genetics of life. The following sites supplement Chapter 17 and also provide additional perspectives on the scientific status and societal debates of genetic engineering.


17.1 Using Recombinant DNA Techniques to Manufacture ProteinsRecombinant DNA Techniques in Biochemistry
Using recombinant DNA techniques, we can produce biological molecules, such as insulin, by inserting the gene for the production of the protein into bacteria or insects, and then growing the host organisms and harvesting the chemicals. This Access Excellence site describes the basics of recombinant DNA technology, and discusses the many ethical issues surrounding its use. Follow the link at the bottom of the page to "Transfer and Cloning of the Insulin Gene" to learn about one common application of this technology.
Keywords: recombinant DNA, insulin, biochemistry

17.2 Gene Hunting Based on Pedigree Analysis

Cystic Fibrosis Carrier: More Information
One of the many inherited genetic diseases our medical community deals with is cystic fibrosis, with 1 in 25 to 30 people being carriers. This site describes the genetics and medicine of the disease. Follow the links throughout the site to learn more about this autosomal recessive disease.
Keywords: cystic fibrosis, autosomal recessive, genetic markers

Rare Genetic Diseases in Children: Detection
Rare genetic diseases in children occur as a result of parents passing on defective genetic material to their offspring. This site details the methods doctors use to clinically seek out the source of a genetic disease and how they develop and prescribe therapies.
Keywords: genetic disease, mutation analysis

17.3 Can Gene Therapy Cure Inherited Diseases in Humans?Medical Ethics: Gene Therapy
Gene therapy is a hot topic in today’s medical and scientific fields. This site presents several articles on the ethics and implications of gene therapy. These articles discuss the perils and promise of this research.
Keywords: gene therapy, ethics, genetic testing

Gene Therapy, the First Decade
Gene therapy as a viable medical therapy has been researched and discussed since the advent of molecular biology techniques. This article discusses the important research and state of knowledge covering studies in gene therapy for the last ten years.
Keywords: gene therapy, history, genetic engineering

17.4 Biotechnology in Agriculture Harvest of Fear: PBS Presentation on Transgenic Crops
Genetically modified food products are among the technologies that our current abilities in molecular biology provide for. This site, from the Public Broadcasting Service (PBS), discusses the major benefits and risks of GMO consumption. Follow the links to learn about current issues in GMO production and consumption and to take part in an online discussion on the topic.
Keywords: GMO, food consumption, organic

Transgenic Crops: A Balanced Overview
Transgenic crops, a type of genetically modified food, give farmers more options in the productivity of their labors, like the luxury of using less pesticide while increasing yields. This site contains a balanced review of the arguments for and against using transgenic crops.
Keywords: transgenic crops, regulation, genetically modified organisms

Organic Food
This site discusses the arguments against the genetic engineering of food organisms and plants. Follow the links to see how the philosophical, medical, ethical, and scientific arguments for strictly regulating how we genetically engineer our food stack up against those who are for such technology.
Keywords: organic, genetically modified food, safety

Genetic Engineering and Its Dangers: Philosophy Essays
Genetic engineering, genetically modified foods, and gene therapy are scientific technologies that are embroiled in philosophical and religious debate. This site lists a collection of articles written by faculty and students at San Franscisco State University on the religious, philosophical, and technical aspects of genetic engineering.
Keywords: philosophy, genetically modified foods, gene therapy

EPA and Biotechnology Crops
Genetic modification, as discussed in the chapter, is one of several ways biotechnology is used to modify food and other crops. This site describes a pending review by the EPA on the registration process of all biotechnology modified crops.
Keywords: GMO, biotechnology, agriculture




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