Chapter 11: Activities
Activity 11.1 One Gene to One Enzyme
Explore the experiments that answered one of the central questions defining molecular biology in the twentieth century: "How do genes work?" One clear answer to this question came from the work of George Beadle and Edward Tatum. These scientists performed a series of experiments on the bread mold, Neurospora crassa, that led them to propose their one-gene, one-enzyme hypothesis. In this activity, youll examine Beadle and Tatum's experiments to (1) isolate mutants in arginine biosynthesis in Neurospora, (2) test whether the mutations affected arginine synthesis, and (3) establish the order of reactants in the arginine biosynthetic pathway.
Chapter 11, Section 11.2, What Do Genes Do?