Biological Science

Chapter 11: Activities

Activity 11.1 One Gene to One Enzyme

CDA11_1.jpg Explore the experiments that answered one of the central questions defining molecular biology in the twentieth century: "How do genes work?" One clear answer to this question came from the work of George Beadle and Edward Tatum. These scientists performed a series of experiments on the bread mold, Neurospora crassa, that led them to propose their one-gene, one-enzyme hypothesis. In this activity, you’ll examine Beadle and Tatum's experiments to (1) isolate mutants in arginine biosynthesis in Neurospora, (2) test whether the mutations affected arginine synthesis, and (3) establish the order of reactants in the arginine biosynthetic pathway.

Prequiz
Introduction to Neurospora
Mutating Neurospora
Finding Nutritional Mutants
Metabolic Pathways
Postquiz

Chapter 11, Section 11.2, What Do Genes Do?





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