| 1. |
Many questions about fertilization and early development remain unanswered:
- Is there a protein on the sperm head of mammals that binds specifically to ZP3 in the zona pellucida?
- How does the entry of sperm cause Ca2+ to be released from intracellular stores, so that polyspermy will be blocked?
- How are cytoplasmic determinants and factors other than Vg1 localized to specific regions of the egg? How is yolk localized to particular regions of the egg?
- In frogs, why and how does the organizer form opposite the point of sperm entry?
- If the zygotic genome is transcribed at the two-cell stage in mammals, do cytoplasmic determinants play a significant role in early development?
- What forces cause cells to move during gastrulation?
Choose one of these questions and design an experiment that would contribute to answering it.
To create paragraphs in your essay response, type <p> at the beginning of the paragraph, and </p> at the end.
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| 2. |
Suppose you are a physician at a fertility clinic. A couple comes to you for assistance with becoming pregnant. The woman is 41 years old, and the man has a low sperm count. Based on the information in this chapter, which treatment would you recommend and why?
To create paragraphs in your essay response, type <p> at the beginning of the paragraph, and </p> at the end.
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