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Early Development > Research Links
In Chapter 19, "Early Development," you
reviewed the early developmental and molecular changes that occur in sexual reproduction,
from the production of gametes in the male and female to gastrulation, in which the first
cell layers are laid down in the early embryo. The following sites review the material
presented in the chapter, provide tutorials and study guides, link to scientific societies
that study some of the biology of these early developmental events, and describe the life
and work of a few of the historical and current researchers in the field.
19.1 Gametogenesis Topics
on Gametogenesis
This site provides links to various other sites that cover
topics in gametogenesis in both the male and female. Follow the "Patterns of
messenger RNA localization" link to review topics on the distribution of cytoplasmic
factors.
Keywords: gametogenesis, cytoplasmic factors, spermatogenesis,
oogenesis
Gametogenesis in
Sea Urchins
Dr. Charles Walker, at the University of New Hampshire, studies
the gametogenesis and early development of sea urchins. His research site discusses
several aspects of early development related to those discussed in the chapter, including
the normal and abnormal production of sperm and eggs.
Keywords: gametogenesis,
sea urchin, early development
Genetic
Control of Ovule Development
As discussed in the chapter, chemical
interactions within and between cells regulate the molecular biology of different cell
groups in development. This article focuses on the interactions between cell layers in
Arabidopsis, describing some of the molecular interactions that are involved in the
genetics of oogenesis.
Keywords: spermatogenesis, oogenesis, genetic
regulation, early development
19.2 Fertilization Sea Urchin
Embryology
This site reviews many of the events in the early stages of sea
urchin fertilization and development. Follow the "animations" link for many
images and animations of various stages in early sea urchin embryology, including
gametogenesis and fertilization.
Keywords: sea urchin, embryology,
fertilization
International Council on Infertility Information
Dissemination
Human infertility is an often encountered medical concern in the
Western World. This nonprofit site focuses on explaining the various causes of
infertility, the options that are available for infertile couples wishing to conceive, and
the social and medical implications of human infertility research.
Keywords:
fertilization, human infertility, human medicine
19.3 Cleavage
Cleavage
This section of the Amphibian Embryology Tutorial describes the
cellular and molecular events that take place during the cleavage stage of early
development. Follow the links throughout the cleavage pages to supplement the information
in the chapter, and the links to the other stages of early development.
Keywords: cleavage, Xenopus, early development, embryology
Center for the Study of Multiple
Births
During the early stages of cleavage, a disturbance that separates the
developing embryo into two or more balls of totipotent cells may lead to twins, triplets,
or even more genetically identical offspring. This site describes how the Center for the
Study of Multiple Births studies the medicine, biology, and sociology of multiple
births.
Keywords: cleavage, multiple births, embryology, early
development
19.4 Gastrulation
Gastrulation Lab
Dr.
Eddy De Robertis studies the molecular changes and cell division events that occur during
Xenopus gastrulation. This lab site describes his research and work, including
descriptions of the transcription factors and signaling chemicals that his lab works
with.
Keywords: gastrulation, Xenopus development, embryology
Hans
Spemann
As explained in the chapter, Hans Spemann’s research led to the
elucidation of the cellular organizer responsible for the onset of gastrulation in
amphibians. This Nobel site describes the work for which Spemann was awarded the Nobel
Prize in Physiology or Medicine in 1935.
Keywords: Spemann organizer, history,
gastrulation, Hans Spemann
Cell Adhesion
Cell adhesion, as
mentioned in the chapter, is integral to the mass cell migrations that occur during
gastrulation and other stages of early development. This site provides a central location
for researchers and students looking at the various proteins and molecular mechanisms of
cell adhesion in embryology and other fields of cell biology.
Keywords: cell
adhesion, gastrulation, early development
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2003
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