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Chapter 10: Gene Expression and Regulation Links

The following Web sites are just some of the interesting resources related to inheritance. As you link to the sites, compare and contrast the information on the site with what you have learned in class, from the textbook, and from other sources you have read. Be sure to share interesting sites with your classmates.

1) How Are Genes and Proteins Related?

Beadle and Tatum

The experiments on Neurospora mutants produced the "one gene/one enzyme" hypothesis and won Beadle and Tatum a Nobel Prize in 1958.

Genes

Learn more about genes and their function at this site, a Web page from the "What the Heck Is . . .?" series.

Overview of Transcription and Translation

More details about information flow in cells are given here.

One Gene/One Enzyme

An interesting review of the key experiments of Beadle and Tatum is summarized in this essay.

History of Genetics

A good review of the history of genetics is available here.

Protein Synthesis

This comprehensive site covers all the basics, from DNA to RNA to protein.

2) How Is Information in a Gene Transcribed into RNA?

Gene Expression: Transcription

This site contains some very detailed information about RNA and the steps of gene transcription.

RNA Transcription and Processing

This site provides a brief, illustrated review of RNA transcription and processing.

DNA to RNA

At this site, you will get a complete overview of the process that converts information from DNA into RNA.

3) How Is the Sequence of a Messenger RNA Molecule Translated into Protein?

BioTech Tools

This site presents a very good hyperlinked list of biotechnology tools. Be sure to view the resources related to protein.

The Genetic Code

Another genetic code table is presented here.

FROM RNA TO PROTEIN

At this site, you will get a complete overview of the process that converts information from RNA into protein.

4) How Do Mutations in DNA Affect the Function of Genes?

Human Genetic Disease

This site provides a wealth of resources for information on genetic conditions, as well as links to support and advocacy groups.

Mutant Flies

When we think of mutations, we often imagine horrible monsters of some sort. Mutations can have subtle effects, as those shown here in this gallery of mutant fruit flies.

Mutations

This site reviews the general types of mutations that occur in cells and their potential outcomes.

Sickle-Cell Anemia

Sickle-cell disease is caused by a single mutation in the beta-hemoglobin gene. Find out more at this Family Village site.

Cystic Fibrosis

This Family Village site discusses the genetic disease cystic fibrosis.

5) How Are Genes Regulated?

Gene Regulation

This Web lecture explains the regulation of gene expression in bacteria.

Eukaryotic Gene Regulation

This online textbook features a very approachable section on gene regulation.

Homeobox Genes

Why do the cells in your arms grow fingers instead of toes? Differences in gene expression are the real reason. Find out how mutations that change one body part of a fly (or a mouse) to another are giving us hints about the process. This site is actually for teachers but has plenty of great information for all of us!

Sex Determination

This site describes the genetics of sex determination in humans (and, briefly, some other organisms). If you scroll down the page, there is a picture of cells stained to show the Barr body.