Biology: Life on Earth

Chapter 8: Harvesting Energy: Glycolysis and Cellular Respiration

Essay Challenge

1. In general, describe the process of glycolysis. [Hint]

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2. How does fermentation keep glycolysis going? [Hint]

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3. Compare and contrast fermentation and cellular respiration. [Hint]

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4. How are the three processes of glycolysis, the Krebs cycle, and the electron transport system connected to each other? [Hint]

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5. Suppose you are studying animal cells in culture that are metabolizing glucose. You are able to control exactly how much sugar is added to the culture. You add 50 molecules of glucose. How many molecules of ATP will be formed in the absence of oxygen? How many molecules of ATP will be formed if oxygen is available? [Hint]

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6. Type I diabetes results from too little circulating insulin. Insulin is a hormone that causes an increase in glucose transport into muscle and liver cells. For the patient with Type I diabetes, his/her body cells act as though they are starved of glucose, even though there are high levels of circulating glucose in the bloodstream. What is the effect of Type I diabetes on cell respiration? Be as specific as possible. [Hint]

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7. A patient with uncontrolled diabetes will often begin to break down fatty acids to acetyl CoA, and use acetyl CoA for cell respiration. During fat breakdown, carbon atoms are removed two carbons at a time and converted to acetyl CoA. How many NADH, FADH2 and ATP will result from the breakdown of sixteen-carbon palmitic acid? [Hint]

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8. Suppose you are performing an experiment in which you are collecting the products of cell respiration from a culture of cells. If you begin with glucose that has radioactive carbon atoms, what product(s) from cell respiration would contain the radioactive carbon? [Hint]

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9. The chemiosmotic hypothesis explains the production of ATP in both photosynthesis and cell respiration as the result of a hydrogen ion gradient. Compare and contrast mitochondria and chloroplasts as to: (a) the location of the electron transport system connected to ATP production (b) the location of the buildup of H+ ions and (c) the function of the ATP that is formed. [Hint]

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