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Objectives

  1. Explain the applications of pharmacokinetics to clinical practice.
  2. Identify the four components of pharmacokinetics.
  3. Explain how substances travel across plasma membranes.
  4. Discuss factors affecting drug absorption.
  5. Explain the metabolism of drugs and its applications to pharmacotherapy.
  6. Discuss how drugs are distributed throughout the body.
  7. Describe how plasma proteins affect drug distribution.
  8. Identify major processes by which drugs are excreted.
  9. Explain how enterohepatic recirculation might affect drug activity.
  10. Explain the applications of a drug’s plasma half-life (t1/2) to pharmacotherapy.
  11. Explain how a drug reaches and maintains its therapeutic range in the plasma.
  12. Differentiate between loading and maintenance doses.





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