

- Explain the applications of pharmacokinetics to clinical practice.
- Identify the four components of pharmacokinetics.
- Explain how substances travel across plasma membranes.
- Discuss factors affecting drug absorption.
- Explain the metabolism of drugs and its applications to pharmacotherapy.
- Discuss how drugs are distributed throughout the body.
- Describe how plasma proteins affect drug distribution.
- Identify major processes by which drugs are excreted.
- Explain how enterohepatic recirculation might affect drug activity.
- Explain the applications of a drug’s plasma half-life (t1/2) to pharmacotherapy.
- Explain how a drug reaches and maintains its therapeutic range in the plasma.
- Differentiate between loading and maintenance doses.